Abstract：Objective To examine the relationship between preconceptional heart rate (HR) and the risk of preterm delivery (PTD). Methods We conducted a historical cohort study consisting of 369 507 rural reproductive-aged women who participated in the National Free Pre-pregnancy Checkups (NFPC) in 2010-2012 and had a live birth before Oct 2013. Data on HR, blood pressure, history of pregnancy and diseases, fasting glucose level, and other variables were obtained from the physical examination record in NFPC. Follow-up evaluation was conducted from June 2010 to Oct 2013. Successful conception and pregnancy outcomes were documented during the follow-up period. In the present study, self-reported PTD was the end point of observation. Multivariate logistic regression models were undertaken to adjust baseline variables with PTD as the outcome variable. Results By the end of September 2013, 3 335 PTD events were documented. Compared to the participants with a heart rate of 70-79 bpm, women with a heart rate of <60, 60-69, 80-89, 90-99, 100-109, and ≥110 bpm had higher risk of PTD, and the corresponding multivariate-adjusted ORs and 95% confidence intervals (CIs) were 1.85 (1.02-3.37), 1.35 (1.19-1.53), 1.01 (0.92-1.10), 1.20 (1.00-1.44), 1.51 (1.12-2.04) and 1.78 (1.08-2.94), respectively. Conclusion Preconception heart rate was associated with risk of PTD risk. Either preconception heart rate <70 bpm or ≥100 bpm confers a risk of PTD.
杨英, 彭左旗, 马旭. 育龄女性孕前心率水平与早产发生风险的相关性[J]. 中国生育健康杂志, 2015, 26(3): 197-201.
YANG Ying, PENG Zuoqi, MA Xu. Preconception heart rate and risk of preterm delivery in Chinese reproductive-aged women. Chinese Journal of Reproductive Health, 2015, 26(3): 197-201.
