1 苏应宽,徐增祥,江森.实用产科学.第2版.济南:山东科学技术出版社,2004:272. 2 季玉琴,张玉泉.胚胎停止发育病因与机制的研究进展.现代妇产科进展,2010,19:146-148. 3 柴冬宁.胚胎停育相关因素研究.中国优生与遗传杂志,2005,13:72-73. 4 刘春兰,柳金梅,王月霞.胚胎停育的原因分析.甘肃医药,2010,29:524-527. 5 Demir R,Seval Y,Huppenz B.Vasculogenesis and angiogenesis in the early human placenta.Acta Histochem,2007,109:257-265. 6 Krussel JB,Behr B,Milki AA,et al.Vascular endothelial growth factor Mrna splice variants are diferentially expressed in human blastocysis.Mol Hum Reprod,2001,7 :57-63. 7 Demir R,Kayisli UA,Cayli S,et al.Sequential steps during vasculogenesis and angiogenesis in the very early human placenta.Placenta,2006,27:535-539. 8 Benirschke K,Kaufmann P.Pathology of the human placenta.New York:Springer,2000. 9 Huppertz B,Weiss G,Moser G.Trophoblast invasionand oxygenation of the placenta:measurements versus presumptions.J Reprod Immunol,2014,101-102:74-79. 10 王为男.早期自然流产患者绒毛组织血管生成状况与超微结构的研究.中南大学,2010. 11 叶俊英,谢建渝.异位妊娠早期诊断标志物的研究进展.检验医学与临床,2006,3:378-380. 12 Zygmunt M,Herr F,Münstedt K,et al.Angiogenesis and vasculogenesis in pregnancy.Eur J Obstet Gynecol Reprod Biol,2003,110 :S10-18. 13 Peirce SM,Price RJ,Skalak TC.Spatial and temporal control of angiogenesis and arteria lization us ing focal applications of VEGF164 and Ang-1.Am J Physiol Heart Circ Physiol,2004,286:H918-925. 14 焦贵霞,郭宏,张新东,等.促血管生成素在子宫内膜中的表达及其对早期妊娠自然流产的影响.山东医药,2008,48:79-80. 15 张翀,孙家邦.胎盘生长因子的病理学作用.国际外科学杂志,2008,35:711 16 董枫,侯灵彤.Caspase-3和PLGF在早期胚胎停止发育患者绒毛和蜕膜组织中的表达.中国妇幼保健,2011:4235-4237. 17 孙澜栩,黄学惠,黄燕,等.稽留流产绒毛中HIF-1α、VEGF 和PLGF 的表达及意义.现代妇产科进展,2013,22:367-372. 18 Anderson UD,Olsson MG,Kristensen KH,et al.Review:Biochemical markers to predict preeclampsia.Placenta,2012,33:S42-47. 19 庞丽红,李敏清,杨冬梅,等.可溶性血管内皮生长因子受体-1( sFlt-1) 与不明原因复发性流产的相关性研究.生殖与避孕,2011,31:59-61. 20 Roberts JM,Rajakumar A.Preeclampsia and soluble fms-like tyrosine kinase 1.J Clin Endocrinol Metab,2009,94:2252-2254. 21 Saito T,Takeda N,Amiya E,et al.VEGF-A induces its negative regulator,soluble form of VEGFR-1,by modulating its alternative splicing.FEBS Letters,2013,587:2179-2185. 22 Nevo O,Soleymanlou N,Wu Y,et al.Increased expression of sFlt-1 in in vivo and in vitro models of human placental hypoxia is mediated by HIF-1.Am J Physiol Regul Integr Comp Physiol,2006,291:R1085-1093. 23 Zhou CC,Ahmad S,Mi T,et al.Angiotensin II induces soluble fms-Like tyrosine kinase-1 release via calcineurin signaling pathway in pregnancy.Circ Res,2007,100:88-95. 24 George EM,Cockrell K,Adair TH,et al.Regulation of sFlt-1 and VEGF secretion by adenosine under hypoxic conditions in rat placental villous explants.Am J Physiol Regul Integr Comp Physiol,2010,299:R1629-1633. 25 Fan X,Rai A,Kambham N,et al.Endometrial VEGF induces placental sFLT1 and leads to pregnancy complications.J Clin Invest,2014,124:4941-4952. 26 Maynard SE,Min JY,Merchan J,et al.Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction,hypertension,and proteinuria in preeclampsia.J Clin Invest,2003,111:649-658. 27 Nagamatsu T,Fujii T,Kusumi M,et al.Cytotrophoblasts up-regulate soluble fms-like tyrosine kinase-l expression under reduced oxygen:an implication for the placental vascular development and the pathophysiology of preeclampsia.Endocrinology,2004,145:4838-4845. 28 周琼,乔福元,刘海意,等.缺氧对滋养细胞sFlt-1及VEGF基因及蛋白表达的影响.生殖与避孕,2010,30:300-303.
