妊娠晚期细菌性阴道病的筛查和治疗与胎膜早破的关系

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摘要目的探讨妊娠晚期细菌性阴道病(BV)的筛查和治疗与胎膜早破的关系。方法选择2017年1月～12月于本院分娩的1 063例单胎孕妇,其中胎膜早破组194例,无胎膜早破组869例;回顾性分析孕妇妊娠晚期(孕28～32周)BV的发病及治疗情况,评价孕晚期BV筛查和治疗与胎膜早破的关系。结果 1 063例孕妇中,BV共65例,其中胎膜早破组13例,非胎膜早破组52例,两组BV发生率分别为6.7%和6.0%,差异无统计学意义。65例BV中,患者要求治疗的28例,阴道放置甲硝唑栓1粒 Qd×7 d,其胎膜早破的发生率为14.3%;患者拒绝治疗的37例,发生胎膜早破的发生率是24.3%;两者差异无统计学意义。结论孕晚期BV的发病和治疗与胎膜早破无明显的相关性,对BV进行阴道局部用药治疗后,胎膜早破的发生率有所降低,但两者差异无统计学意义。

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	王静
	刘海燕
	李智
	蔺莉

关键词 ：阴道微生态, 细菌性阴道病, 胎膜早破

Abstract：Objective To investigate the relationship between screening and treatment of bacterial vaginosis among pregnant women in their third trimester and premature rupture of membranes. Methods 1 063 cases of pregnant women with singleton birth from January 2017 to December 2017 in our hospital were enrolled. Among which, 94 cases were PROM (premature rupture of membranes), 869 cases were non-PROM. To investigate the relationship between RPOM and BV, the prevalence of bacterial vaginosis (BV) and the treatment in their third trimester (28-32 gestational weeks) was analyzed. Results There were a total of 65 BV patients in the study. The incidence of BV in the PROM group and the non-PROM group was 6.7% and 6.0%, respectively, with no statistical difference between the two groups. 28 cases were treated with vaginal Metronidazole suppository (Qd*7 days) in the BV group and 37 cases were not treated. The rates of PROM in the treated group and untreated group was 14.3% and 24.3% respectively, with no statistical difference observed between the two groups. Conclusion The screening and treatment of BV in the third trimester was not correlated with risk of PROM. The prevalence of PROM is slightly lower after BV treatment, but there was no statistical difference.

Key words： vaginal microecology, bacterial vaginosis (BV) premature rupture of membranes (PROM)

收稿日期: 2018-02-08

通讯作者: 蔺莉(linli488@aliyun.com)

引用本文:

王静, 刘海燕, 李智, 蔺莉. 妊娠晚期细菌性阴道病的筛查和治疗与胎膜早破的关系[J]. 中国生育健康杂志, 2018, 29(4): 324-326.
WANG Jing, LIU Haiyan, LI Zhi, LIN Li. Relationship between screening and treatment of bacterial vaginosis among pregnant women in their third trimester and premature rupture of membranes. Chinese Journal of Reproductive Health, 2018, 29(4): 324-326.

链接本文:

http://cjrh.bjmu.edu.cn/CN/ 或 http://cjrh.bjmu.edu.cn/CN/Y2018/V29/I4/324

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