生物补片法阴道成形术治疗先天性无阴道的疗效分析

摘要
图/表
参考文献
相关文章 (0)

全文: PDF (724 KB) HTML (1 KB)
输出: BibTeX | EndNote (RIS)

摘要目的探讨采用生物补片法阴道成形术治疗先天性无阴道(Mayer-Rokitansky-Küster-Hauser,MRKH)综合征的疗效。方法选取2006—2013年广东省佛山市妇幼保健院妇科住院收治的15例 MRKH 综合征患者作为研究对象,均采用生物材料[人工脱细胞真皮(acelluar dermal matrix allograft,ADM)]行人工阴道成形术,对其术中、术后及随访情况进行分析。结果 15例患者手术均顺利完成,术中和术后均无严重不良反应发生,手术平均时间(69.4±13.6)min,术中平均出血量(50.6±15.3)ml,术后排气时间(57.7±13.2)h,术后平均住院时间(33.9±5.9)d,住院平均费用(15 683.9±1 111.8)元。结论生物补片法人工阴道成形术能够有效地治疗先天性无阴道综合征,手术方式理想、安全、有效,为患者重塑一个在解剖上、功能上接近正常的人工阴道,值得在临床上推广和应用。

	服务

	把本文推荐给朋友
	加入我的书架
	加入引用管理器
	E-mail Alert
	RSS
	作者相关文章
	江卓飞
	柳晓春
	谢庆煌
	郑玉华
	汪洪

关键词 ：先天性无阴道综合征, 生物补片, 阴道成形术

Abstract：Objective To evaluate the efficacy of vaginoplasty using tissue-engineered biomaterial mesh in patients with Mayer -Rokitansky-Küster-Hauser (MRKH) syndrome. Methods This study included 15 patients with MRKH admitted to Foshan Women and Children’s Hospital in recent years. These patients received vaginoplasty with tissue-engineered biological material (acellular dermal matrix allograft, ADM). Operation process, postoperative complication and other characteristics were reviewed. Results No severe adverse complications were observed during and after operation. The average operation time was (69.4±13.6) min; mean volume of bleeding during operation was (50.6±15.3) ml; mean time of intestinal gas release after operation was (57.7±13.2) h; mean days of hospital stay after operation were (33.9±5.9) days; and the average cost of hospitalization was (15 683.9±1 111.8) yuan RMB. Conclusion Tissue-engineered biomaterial mesh is effective in the treatment of MRKH. This treatment modality appears safe and effective. The man-made vagina in the basic body is close to the normal vaginal and can satisfy the patient’s sexual needs.

Key words： Mayer-Rokitansky-Küster-Hauser syndrome Tissue-engineered biomaterial mesh Vaginoplasty

收稿日期: 2015-02-28

通讯作者: 柳晓春(jiangzhuofei020@126.com)

引用本文:

江卓飞, 柳晓春, 谢庆煌, 郑玉华, 汪洪. 生物补片法阴道成形术治疗先天性无阴道的疗效分析[J]. 中国生育健康杂志, 2015, 26(4): 312-315.
JIANG Zhuofei, LIU Xiaochun, XIE Qinghuang, ZHENG Yuhua, WANG Hong. Outcomes in patients with MRKH syndrome undergone vaginoplasty using tissue-engineered biomaterial mesh. Chinese Journal of Reproductive Health, 2015, 26(4): 312-315.

链接本文:

http://cjrh.bjmu.edu.cn/CN/ 或 http://cjrh.bjmu.edu.cn/CN/Y2015/V26/I4/312

1 姚丽萍.先天性无阴道手术 8例分析.中国现代医生,2009,47:128-129.
2 Abramowicz S,Oden S,Joutel N,et al.Laparoscopic creation of a neovagina by Vecchietti’s technique:anatomic and functional results.Gynecol Obstet Fertil,2013,41:4-9.
3 周慧梅,朱兰.先天性无阴道综合征生物补片法阴道成形术的手术方法介绍和临床结局.中国计划生育和妇产科,2013,5:9-13.
4 李文娟.先天性无阴道的治疗进展.医学临床研究,2011,28:532-534.
5 Rosen R,Brown C,Heiman J,et al.The Female Sexual Function Index (FSFI):A multidimensional self - report instrument for the assessment of female sexual function.J Sex Marital Ther,2000,26:191-208.
6 朱兰,周慧梅,郎景和.组织工程医用补片在人工阴道成形术中的应用.中国实用妇科与产科杂志,2006,22:953-954.
7 Fotopoulou C,Sehouli J,Gehrmann N,et al.Functional and anatomic results of Amnion vaginoplasty in young women with Mayer -Rokitansky - Küster - Hauser syndrome.Fertil Steril,2010,94:317-323.
8 李宝艳,杜敏,廖莳,等.罗湖Ⅱ式腹腔镜腹膜阴道成形术临床应用研究.中国妇幼保健,2011,26:1712-1715.
9 李雅钗,高新萍,黄向华.先天性无阴道的治疗进展和临床评估.医学研究与教育,2014,31:70-78.
10 Ehrenreich M,Ruszczak Z.Update on dermal substitutes.Acta Dermatovenerol Croat,2006,14:172-187.
11 Carrard C,Chevret - Measson M,Lunel A,et al.Sexuality after sigmoid vaginoplasty in patients with Mayer-Rokitansky-Küster-Hauser syndrome.Fertil Steril,2012,97:691-696.
12 Edmonds DK.Congenital malforlfflations of the genital tract and theirmanagement .Best Pract Res Clin Obstet Gynecol,2003,17:19-40.
13 Ghanbari Z,Dahaghin M,Borna S.Long-term outcomes of vaginal reconstruction with and without amnion grafts.Int J Gynaecol Obstet,2006,92:163-164.
14 Zhou JH,Sun J,Yang CB,et al.Long-term outcomes of transvestibular Vaginoplasty with pelvic peritoneum in 182 patients with Rokitansky’ s syndrome.Fertil Steri,2010,94:2281-2285.