Abstract：Objective To explore the dynamic prevalence of neural tube defects in Fangshan district of Beijing from 2006 to 2012. Methods Data collected through routine birth defects surveillance system in Fangshan district during 2006 and 2012 were used. The dynamic prevalence, distribution by population characteristics and the proportions of prenatal diagnosis of neural tube defects were analyzed. Results From 2006 to 2012, 61 neural tube defects were identified among 50 234 births, with a prevalence of 12.1 per 10 000. The prevalence of anencephaly, spina bifida and encephalocele was 5.4 per 10 000, 4.8 per 10 000 and 2.0 per 10 000, respectively. The prevalence of neural tube defects of the floating population (20.0 per 10 000) was 2.3 times higher than that of the permanent local residents (8.8 per 10 000). After the implementation of folic acid supplementation program in 2009, the prevalence of neural tube defects among floating population showed a downward trend during 2010 to 2012, but the prevalence among permanent residents rebounded in 2012. The proportion of prenatal diagnosis of neural tube defects was 80.0% from 2006 to 2012, and the proportion of prenatal diagnosis before 28 gestational weeks was 68.3%. Conclusion The prevalence of neural tube defects in Fangshan district was slightly higher than the prevalence of Beijing and some of its districts. Moreover, the prevalence of neural tube defects of the floating population was higher than that of the permanent residents. Education and management of folic acid supplementation before pregnancy need to be strengthened. Moreover, the ability of prenatal diagnosis of neural tube defects in this district needs to be improved.
马瑞新, 杨燕芬, 刘辉, 靳蕾. 2006—2012年北京市房山区神经管缺陷流行特征[J]. 中国生育健康杂志, 2015, 26(4): 316-319.
MA Ruixin, YANG Yanfen, LIU Hui, JIN Lei. Epidemiological characteristics of neural tube defects in Fangshan district of Beijing from 2006 to 2012. Chinese Journal of Reproductive Health, 2015, 26(4): 316-319.
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