Abstract：Objective To evaluate the changes of ovarian function after ultrasound (US)-guided percutaneous microwave ablation (PMWA) in the treatment of adenomyosis. Methods PMWA was performed on 87 premenopausal women with symptomatic adenomyosis. Estradiol (E2) and follicle-stimulating hormone (FSH) were recorded before and after ablation 3, 6, 9 and 12 menstrual cycles. Clinical signs of the menopausal transition and fertility related informations were also noted. Results There were no statistical differences in E2 and FSH between pre-ablation and all the recheck points. Uterine amenorrhea was observed in 1 patient. Four patients conceived once and 1 patient conceived twice after PMWA. Conclusion There is no evidence indicated a damage of ovarian function, but the observation on fertility function needs further studies.
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