Abstract：Objective To assess the value of prenatal ultrasound system screening for congenital malformations.Methods Data of prenatal screening results for 2 056 women with singleton pregnancy in our hospital from January 2010 through December 2012 were analyzed. Fetal outcomes were ascertained through autopsy, physical examination and chromosome test. Sensitivity, specificity, positive predictive value and negative predictive value of prenatal ultrasound screening system for congenital malformations were calculated.Results Of the 2 056 fetuses, 86 fetuses were diagnosed as having a defect. Of the 86 fetuses, prenatal ultrasound correctly detected 75 cases, resulting in sensitivity of 87.2% and specificity of 99.8%, positive predictive value of 93.8%, negative predictive value of 99.4%, as well as the clinical diagnosis consistent rate of 99.2%. For major structural deformities, the sensitivity was 94.1%, specificity 99.9%, positive predictive value 98.0%, negative predictive value 99.9%, as well as the clinical diagnosis consistent rate 99.9%.Conclusion Prenatal ultrasound system screening for congenital malformations is valuable in detecting major fetal defects.
隋霜, 朱丽红, 张艳梅. 产前系统超声检查对先天畸形的筛查效果评价[J]. 中国生育健康杂志, 2014, 25(4): 319-321.
SUI Shuang, SONG Xiaoping, ZHANG Yanmei. Clinical value of prenatal ultrasound system screening for fetal structural defects. Chinese Journal of Reproductive Health, 2014, 25(4): 319-321.
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