表观遗传学与精子发生、胚胎发育相关性

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摘要表观遗传学指的是并不涉及核酸序列的改变,基因在有丝分裂和减数分裂的过程中发生的改变可具有遗传性的一门遗传学新兴学科。目前的研究主要集中在染色体重塑(chromatin remodeling)、组蛋白乙酰化、DNA甲基化(DNA methylation)和非编码RNA(non-coding RNA)调控等方面。近几年来,通过对表观遗传学的不断探索,发现多种生殖障碍,如精子发生、胚胎发育的发生发展与其相关。

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	王青青
	李永刚

关键词 ：染色体重塑, 组蛋白乙酰化, 非编码RNA, DNA甲基化, 表观遗传学

收稿日期: 2016-06-20

通讯作者: 李永刚(ygli232@vip.sina.com)

引用本文:

王青青, 李永刚. 表观遗传学与精子发生、胚胎发育相关性[J]. 中国生育健康杂志, 2016, 27(6): 596-598.

链接本文:

http://cjrh.bjmu.edu.cn/CN/ 或 http://cjrh.bjmu.edu.cn/CN/Y2016/V27/I6/596

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