精子形态学特定缺陷与运动特征的相关性研究

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摘要目的探讨精子活力与具体形态学缺陷的相关性,以评估目前精子形态学标准的诊断价值。方法常规采集精液标本,参照世界卫生组织手册的标准进行精液常规分析和精子形态学应用评估,对具体精子形态异常与精子活力数据进行相关性分析。结果活动精子百分率分别与小顶体、头颈弯曲、短尾、卷尾呈显著负相关(P<0.01),前向运动精子百分率与圆头、梨形头、小顶体、头颈弯曲、短尾、卷尾呈显著负相关(P<0.05),精子游动速度与锥形头、梨形头、不规则头、小顶体、头颈弯曲、短尾、卷尾呈显著负相关(P均<0.01),有效精子浓度与圆头(P<0.05)、梨形头、不规则头、小顶体、头颈弯曲、短尾、尾部弯折、卷尾呈显著负相关(P<0.01),而颈部异常粗与以上各个活力参数呈显著正相关(P<0.01)。结论目前对精子形态缺陷的分类具有一定的诊断价值,但仍需进一步改进。

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	沈丽燕
	余怡
	王家雄
	杨慎敏
	王玮
	李红

关键词 ：精子形态, 精子活力, 男性不育

收稿日期: 2018-07-12

基金资助:苏州市男性生殖研究重点实验室(SZS201718); 苏州市临床医学中心(Szzx201505); 苏州市科教兴卫青年科技项目(KJXW2017028)

引用本文:

沈丽燕, 余怡, 王家雄, 杨慎敏, 王玮, 李红. 精子形态学特定缺陷与运动特征的相关性研究[J]. 中国生育健康杂志, 2019, 30(5): 471-474.

链接本文:

http://cjrh.bjmu.edu.cn/CN/ 或 http://cjrh.bjmu.edu.cn/CN/Y2019/V30/I5/471

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