光动力治疗外阴硬化性苔藓的研究进展

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摘要外阴硬化性苔藓(VLS)是一种好发于外阴、肛周,以外阴瘙痒、烧灼感为主要症状,以皮肤粘膜萎缩变薄、色素减退呈白色病变为主要特征的慢性炎症性疾病。目前VLS以局部药物治疗为主,多数治疗有效但不能治愈且容易复发,因此寻找新的切实有效的治疗方法仍是学术界的难题。光动力治疗(PDT)是浓集于病变组织细胞中的光敏剂受到特定波长光源照射激发后,发生一系列光化学反应诱导细胞凋亡、破坏病变组织及其微环境从而治疗疾病的方法。目前主要用于治疗多种恶性肿瘤、皮肤疾病,近年来临床上使用PDT治疗VLS取得了一定的进展,以其创伤小、不良反应少、治疗后不易复发等特点,有望成为VLS治疗的新方法。本文就PDT治疗VLS的现状及进展进行综述。

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	陆皓
	高佳音
	霍利婷
	王路遥
	岳欣
	李佩玲

关键词 ：外阴硬化性苔藓, 光动力治疗, 疗效

收稿日期: 2018-07-03

基金资助:国家重点研发计划项目(2017YFB0403800)

通讯作者: 李佩玲(peiley@126.com)

引用本文:

陆皓, 高佳音, 霍利婷, 王路遥, 岳欣, 李佩玲. 光动力治疗外阴硬化性苔藓的研究进展[J]. 中国生育健康杂志, 2020, 31(1): 90-92.

链接本文:

http://cjrh.bjmu.edu.cn/CN/ 或 http://cjrh.bjmu.edu.cn/CN/Y2020/V31/I1/90

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