Abstract：Objective To study the changes of laboratory indexes of HELLP syndrome before and after delivery. Methods Information on 127 patients with HELLP syndrome who diagnosed and hospitalized in Peking University Third Hospital from December 2008 to November 2018 were analyzed retrospectively. The fasting blood of the patients were collected and the routine blood test, liver and renal function were monitored dynamically. Results The patients with HELLP syndrome accounted for 0.4% of the total parturients in our hospital at the same period, including 74 cases of complete HELLP syndrome, 53 cases of partial HELLP syndrome, 94 cases of prenatal HELLP syndrome and 33 cases of postpartum HELLP syndrome. The platelet count in the complete HELLP group was significantly lower than that in the partial HELLP group (P<0.05), and the total bilirubin (TBIL) and aspartate transaminase (AST) in the complete HELLP group and lactate dehydrogenase (LDH) were significantly higher than partial HELLP group (P<0.05); there was a significant difference in serum creatinine (Cr) between the two groups (P<0.01). In 94 cases of prenatal HELLP syndrome, the platelet and liver function of 92 cases began to recover in 24 hours postnatal, and returned to normal in 5 days postnatal. Except for on dead case, 32 out of the 33 postnatal HELLP syndrome decreased to the lowest laboratory index in 24-48 hours postnatal, and then gradually recovered. Conclusion Most of the patients with HELLP syndrome recovered to the prepregnancy level on the 5th day after delivery.
