1 Sonek JD,Cicero S,Neiger R,et al.Nasal bone assessment in prenatal screening for trisomy 21. Am J Obstet Gynecol,2006,195:1219-1230. 2 Canda MT,Demir N,Sezer O.Fetal Nasal Bone Length as a Novel Marker for Prediction of Adverse Perinatal Outcomes in the First-Trimester of Pregnancy.Balkan Med J,2017,34:127-131. 3 Wojda KM,Moczulska H,Sieroszewski PJ.The absence of fetal nasal bones in ultrasound examination between 11+0 and 13+6 weeks of gestation versus the occurrence of trisomies 21,18,and 13. Ginekol Pol,2019,90:604-606. 4 李胜利,邓学东.产前超声检查指南(2012).中华医学超声杂志(电子版).2012,9:574-580. 5 Yayla M,Ergin RN,Goynumer G.Normative values of fetal nasal bone lengths of Turkish singleton pregnancies in the first trimester.J Turk Ger Gynecol Assoc,2011,12:225-228. 6 谢红宁,朱云晓,李丽娟,等.胎儿鼻骨超声测量对染色体异常的诊断价值.中华围产医学杂志,2006,9:89-92. 7 Burn SC,Markese A,Bangdiwala A,et al.Fetal nasal bone length in the East African population.J Ultrasound Med,2020,39:1007-1012. 8 谢红宁,朱云晓,李丽娟,等.对妊娠中晚期孕妇行超声检测胎儿鼻骨发育状况以筛查唐氏综合征.中华妇产科杂志,2008,43:171-174. 9 解左平,金社红,李红梅,等.胎儿鼻骨超声检测的临床意义.浙江医学,2009,31:991-992. 10 Hansen L,Skovgaard LT,Nohing D,et al.Human prenatal nasal bone lengths:normal standards and length values in fetuses with cleft lip and cleft palate.Cleft Palate Craniofac J,2005,42:165-170. 11 Du Y,Ren Y,Yan Y,et al.Absent fetal nasal bone in the second trimester and risk of abnormal karyotype in a prescreened population of Chinese women.Acta Obstet Gynecol Scand,2018,97:180-186. 12 Węgrzyn P,Czuba B,Serafin D,et al.Nasal bone in screening for T21 at 11-13 + 6 weeks of gestation - a multicenter study.Ginekol Pol,2016,87:751-754. 13 Gautier M,Gueneret M,Plavonil C,et al.Normal Range of Fetal Nasal Bone Length during the Second Trimester in an Afro-Caribbean Population and Likelihood Ratio for Trisomy 21 of Absent or Hypoplastic Nasal Bone.Fetal Diagn Ther,2017,42:130-136. 14 侯磊,王小新,姜海利,等.鼻骨发育异常胎儿产前诊断结果的分析.中华医学杂志,2018,98:3532-3535. 15 Gu YZ,Nisbet DL,Reidy KL,et al.Hypoplastic nasal bone:A potential marker for facial dysmorphism associated with pathogenic copy number variants on microarray.Prenat Diagn,2019,39:116-123.