1 Navarro-Alarcon M,Cabrera-Vique C.Selenium in food and the human body:a review.Sci Total Environ,2008,400:115-141. 2 曾静,罗海吉.微量元素硒的研究进展.微量元素与健康研究,2003,20:52-56. 3 Thomson CD.Assessment of requirements for selenium and adequacy of selenium status:a review.Eur J Clin Nutr,2004,58:391-402. 4 Kryukov GV,Castellano S,Novoselov SV,et al.Characterization of mammalian selenoproteomes.Science,2003,5624:1439-1443. 5 Mistry HD,Pipkin FB,Redman CW,et al.Selenium in reproductive health.American Journal of Obstetrics and Gynecology,2012,206:21-30. 6 Rayman MP,Bode P,Redman CW.Low selenium status is associated with the occurrence of the pregnancy disease preeclampsia in women from the United Kingdom.Am J Obstetrics Gynecol,2003,189:1343-9. 7 Steegers EA,von Dadelszen P,Duvekot JJ,et al.Pre-eclampsia.Lancet,2010,376:631-644. 8 Hutcheon JA,Lisonkova S,Joseph KS.Epidemiology of pre-eclampsia and the other hypertensive disorders of pregnancy.Best Pract Res Clin Obstet Gynaecol,2011,l25:391 - 403. 9 Shah DM.Preeciampsia:new insight.Curr Opin Nephrol Hypertens,2007,3:213-220. 10 Bellamy L,Casas JP,Hingorani AD,et al.Preeclampsia and risk of cardiovascular disease and cancer in later life:systematic review and meta-analysis.BMJ,2007,7627:974. 11 Valdiviezo C,Garovic VD,Ouyang P.Preeclampsia and hypertensive disease in pregnancy:their contributions to cardiovascular risk.Clin Cardiol,2012,35:160 -165. 12 Kurabayashi T,Mizunuma H,Kubota T,et al.Pregnancy-induced hypertension is associated with maternal history and a risk of cardiovascular disease in later life:Japanese cross-sectional study.Maturitas,2013,75:227-231. 13 Vanderlelie JJ,Perkins AV.Selenium and preeclampsia:a global perspective.Pregnancy Hypertens1,2011,21:213-224. 14 Reena N,Deepti P,Kanchan K,et al.Trace elements and antioxidant enzymes associated with oxidative stress in the pre-eclamptic/eclamptic mothers during fetal circulation.Clinical Nutrition,2012,31:946-950. 15 Ohad K,Ofra P,Tal L,et al.Severe pre-eclampsia is associated with abnormal trace elements concentrations in maternal and fetal blood.Maternal-Fetal and Neonatal Medicine,2012,7:1127-1130. 16 Maleki A,Fard MK,Zadeh DH,et al.The relationship between plasma level of Se and preeclampsia.Hypertension in Pregnancy,2011,30:180-187. 17 Rayman MP,Abou-Shakra FR,Ward NI,et al.Comparison of selenium levels in pre-eclamptic and normal pregnancies.Biol Trace Elem Res,1996,55:9-20. 18 Mahomed K,Williams MA,Woelk GB,et al.Leukocyte selenium,zinc,and copper concentrations in preeclamptic and normotensive pregnant women.Biol Trace Elem Res 2000,75:107-118. 19 吴春春.硒与谷胱甘肽过氧化物酶的关系及其在子痫前期中的作用.医学综述,2008,14:280-281. 20 Rani N,Dhingra R,Arya DS,et al.Role of oxidative stress markers and antioxidants in the placenta of preeclamptic patients.Obstetrics and Gynaecology,2010,6:1189-1194. 21 Rayman MP,Searle E,Kelly L,et al.Effect of selenium on markers of risk of pre-eclampsia in UK pregnant women:a randomised,controlled pilot trial.Bri J Nutr,2014,112:99-111. 22 Rayman MP,Bath SC,Westaway J,et al.Selenium status in UK pregnant women and its relationship with hypertensive conditions of pregnancy.Bri J Nutr,2015,113:249-258. 23 Cengiz B,Sylemez F,ztürk E.Serum zinc,selenium,copper and lead level in women with second-trimester induced abortion resulting from neural tube defects.Biol Trace Elem Res,2004,97:225-235. 24 Watson M,van Leer L,Vanderlelie JJ,et al.Selenium supplementation protects trophoblast cells from oxidative stress.Placenta,2012,33:1012-1019. 25 Tara F,Maamouri G,Rayman MP,et al.Selenium supplementation and the incidence of preeclampsia in pregnant Iranian women:a randomized,double-blind,placebo-controlled pilot trial.Taiwan J Obstet Gynecol,2010,49:181-187. 26 Khera A,Vanderlelie JJ,Perkins AV.Selenium supplementation protects trophoblast cells from mitochondrial oxidative stress.Placenta,2013,34:594-598.