1 Vander Borght M,Wyns C.Fertility and infertility:definition and epidemiology.Clin Biochem,2018,62:2-10. 2 Carson S A,Kallen A N.Diagnosis and management of infertility:a review.Jama,2021,326:65-76. 3 Sun M,Wang R,Zhang H,et al.Molecular cytogenetic characterization of small supernumerary marker 15 in infertile male:A case report.Exp Ther Med,2020,19:2927-2932. 4 Gunes S,Esteves S C.Role of genetics and epigenetics in male infertility.Andrologia,2021,53:e13586. 5 Armanet N,Tosca L,Brisset S,et al.Small supernumerary marker chromosomes in human infertility.Cytogenet Genome Res,2015,146:100-8. 6 Song S H,Park S H,Shin E,et al.Male infertility associated with a supernumerary marker chromosome.World J Mens Health,2017,35:205-208. 7 Donker R B,Vloeberghs V,Groen H,et al.Chromosomal abnormalities in 1663 infertile men with azoospermia:the clinical consequences.Hum Reprod,2017,32:2574-2580. 8 Slimani W,Jelloul A,Al-Rikabi A,et al.Small supernumerary marker chromosomes(sSMC) and male infertility:characterization of five new cases,review of the literature,and perspectives.J Assist Reprod Genet,2020,37:1729-1736. 9 Gao M,Pang H,Zhao Y H,et al.Karyotype analysis in large sample cases from Shenyang Women's and Children's hospital:a study of 16,294 male infertility patients.Andrologia,2017,49. 10 杨兰,张晓,林娟,等.额外小标记染色体的遗传学检测和临床效应分析.中华医学遗传学杂志,2019,36:1047-1050. 11 Manvelyan M,Riegel M,Santos M,et al.Thirty-two new cases with small supernumerary marker chromosomes detected in connection with fertility problems:detailed molecular cytogenetic characterization and review of the literature.Int J Mol Med,2008,21:705-14. 12 俞艇,孙亨秋,陶良艇,等.Y染色体微缺失与男性不育的相关性分析.中国性科学,2020,29:7-10. 13 Karamysheva T,Kosyakova N,Guediche N,et al.Small supernumerary marker chromosomes and the nuclear architecture of sperm - a study in a fertile and an infertile brother.Syst Biol Reprod Med,2015,61:32-6. 14 徐礼臻,朱再生,徐浩.男性生精障碍与染色体异常关系探讨.中国优生与遗传杂志,2020,28:1029-1030. 15 Liehr T,Ewers E,Hamid A B,et al.Small supernumerary marker chromosomes and uniparental disomy have a story to tell.J Histochem Cytochem,2011,59:842-8. 16 孙美玲,王瑞雪,张红国,et al.47,XY,+mar伴男性不育两例.中华医学遗传学杂志,2020,37:1201. 17 Oracova E,Musilova P,Kopecna O,et al.Sperm and embryo analysis in a carrier of supernumerary inv dup(15) marker chromosome.J Androl,2009,30:233-9.