妊娠期糖尿病孕妇和正常孕妇孕期血脂变化的观察性研究

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摘要目的分析妊娠期糖尿病(GDM) 孕妇及正常孕妇孕期各阶段血脂的变化。方法选取2017年1月至2017年6月在北京大学国际医院妇产科分娩的单胎GDM孕妇94例作为病例组,正常孕妇114例为对照组,分别检测两组孕妇孕早、中、晚期血清总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)的水平,比较两组各阶段血脂的差异情况。采用Logistic回归分析GDM发病的高危因素。结果同组孕妇在孕早、中、晚期的TC、TG、HDL-C、LDL-C、TG/HDL-C比较,两者差异有统计学意义;GDM组孕妇各孕期TG、TG/HDL-C明显高于同孕期正常孕妇,HDL-C均明显低于同孕期正常孕妇,差异均有统计学意义。Logistic回归分析发现,孕前BMI、孕中期TG/HDL-C是GDM发病的危险因素。结论正常孕妇及GDM孕妇血脂水平存在明显的差异,孕前及孕期需合理控制体重,加强孕期营养管理及血脂监测。

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关键词 ：妊娠期糖尿病, 血脂, 体重指数

收稿日期: 2017-12-04

通讯作者: 蔺莉(linli488@aliyun.com)

引用本文:

王静, 李菊, 李智, 蔺莉. 妊娠期糖尿病孕妇和正常孕妇孕期血脂变化的观察性研究[J]. 中国生育健康杂志, 2018, 29(2): 154-157.

链接本文:

http://cjrh.bjmu.edu.cn/CN/ 或 http://cjrh.bjmu.edu.cn/CN/Y2018/V29/I2/154

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