胎儿脐血中脂联素水平与出生体重的相关性

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摘要目的探讨胎儿脐血中脂联素水平与出生体重的相关性。方法选择2015年10月—2015年12月在本院分娩的健康新生儿30例,根据新生儿出生体重分为＜3 000 g组、3 000～3 999 g组、≥4 000 g组,分析各组新生儿母亲的年龄、身高、孕次、产次、孕前BMI及新生儿出生体重与母血、脐血脂联素浓度、新生儿性别的关系。结果男婴和女婴脐血中脂联素含量均明显高于其母血中脂联素含量,差异有统计学意义;男婴与女婴母血脂联素浓度比较,差异无统计学意义;女婴脐血脂联素浓度明显高于男婴,差异有统计学意义。母血脂联素浓度与孕母年龄、身高、孕次、产次无关(r=0.043、0.087、0.076、0.101,P＞0.05);母血脂联素与孕前BM1、新生儿性别相关(r=0.365、0.886,P＜0.05)。三组母血脂联素比较,差异无统计学意义;3 000～3 999 g组、≥4 000 g组脐血脂联素水平明显高于＜3 000 g组,差异有统计学意义。新生儿出生体重与母血脂联素浓度无关(r=0.014,P=0.912);新生儿体重与脐血脂联素浓度相关(r=0.939,P＜0.01)。结论胎儿脐血脂联素水平与孕母年龄、身高、孕次、产次无关,与孕前BMI、新生儿性别相关,与出生体重高度相关,可作为胎儿生长发育与营养状态的评价指标之一。

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	江丽萍
	李智泉
	邱诗贤

关键词 ：胎儿脐血, 脂联素, 出生体重, 相关性

Abstract：Objective To investigate the correlation between the adiponectin level in fetal umbilical cord blood and birth weight.Methods 30 cases of healthy newborns delivered in our hospital from October 2015 to December 2015 were selected and were divided into <3 000 g group, 3 000-3 999 g group and ≥4 000 g group according to birth weight. The relationship between mothers’ age, height, gravidity, parity, pregnancy BMI, neonatal birth weight, infant sex, and concentrations of adiponectin in maternal blood and umbilical cord blood was analyzed.Results The levels of adiponectin in umbilical cord blood of both boys and girls were significantly higher than those in maternal serum, and there was a statistically significant difference between male and female infants. There was no significant difference in serum adiponectin concentration between males and females. Umbilical serum adiponectin concentrations in girls were significantly higher than those in boys. Maternal serum adiponectin concentration was not related to the mothers’ age, height, second birth and birth times. Maternal serum adiponectin and BM1 before pregnancy was related to neonatal sex. There was no significant difference in maternal serum adiponectin among the three birth weight groups. Umbilical adiponectin levels in 3 000-3 999 g group and ≥4 000 g group were significantly higher than that of <3 000 g group. Birth weight and umbilical adiponectin concentrations were correlated (r=0.939, P<0.01).Conclusion Umbilical adiponectin levels can be used as one of the indicators of fetal growth and development and nutritional status.

Key words： Umbilical cord blood Adiponectin Birth weight Correlation

收稿日期: 2016-04-09

引用本文:

江丽萍,李智泉,邱诗贤. 胎儿脐血中脂联素水平与出生体重的相关性[J]. 中国生育健康杂志, 2017, 28(1): 46-48.
JIANG Liping, LI Zhiquan, QIU Shixian. Correlation between the adiponectin levels in umbilical cord blood and birth weight. Chinese Journal of Reproductive Health, 2017, 28(1): 46-48.

链接本文:

http://cjrh.bjmu.edu.cn/CN/ 或 http://cjrh.bjmu.edu.cn/CN/Y2017/V28/I1/46

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