Abstract：Objective To identify factors affecting pregnancy rate in patients with poor ovarian response during in vitro fertilization and embryo transfer (IVF-ET/IVF-ICSI) treatment.Methods A total of 1 376 cycles of IVF-ET/IVF-ICSI were analyzed retrospectively by comparing pregnant and non-pregnant women suffering from ovarian poor response.Results There were statistical differences between the two groups with regard to age, years expiring infertility, causes of infertility, surgery history, cycle number, basal sex hormone level, stimulating ovulation protocol, Gn type, hormone level on the day of hCG injection, numbers of oocytes retrieved, numbers of mature oocytes, endothelium thickness on the hCG injection, fertilization rate, embryo cleavage rate, number of embryos transferred, and number of good quality embryos. Multivariate logistic regression showed that age, stimulating ovulation protocol, number of good quality embryos, and embryo morphology were associated with pregnancy.Conclusion Age is the most important factor that affects the pregnant outcome of ovarian poor response. For patients younger than 35 years, the reduction of the number of oocytes retrieved doesn’t mean the reduction of the quality of oocytes. Rather, pregnancy could be achieved after embryos transfer. Among the superovulation induction protocols for patients with certain ovarian reserve, long protocol (including long-lasting protocol and short-long protocol) may be a way to achieve a higher pregnancy rate.
伍园园,洪岭,王奇玲,李昆明,滕晓明. 体外受精-胚胎移植中卵巢反应不良患者妊娠成功率的相关因素分析[J]. 中国生育健康杂志, 2017, 28(1): 42-45.
WU Yuanyuan, HONG Ling, WANG Qiling, LI Kunming, TENG Xiaoming. Factors associated with successful pregnancy in patients with poor ovarian response during in vitro fertilization and embryo transfer. Chinese Journal of Reproductive Health, 2017, 28(1): 42-45.
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