Abstract:Objective To assess anxiety and depression levels in women before and after undergoing invasive prenatal diagnostic procedures.Methods A prospective study was carried out from June 2014 to October 2014 at the Department of Prenatal Diagnosis and Fetal Medicine, The Third Affiliated Hospital of Guangzhou Medical University. Questionnaires were administered to women scheduled for invasive prenatal diagnostic procedures (n=170). The questionnaires included three parts: general information, cognitive questionnaire about invasive procedures, and the Hospital Anxiety and Depression Scale (HAD). The HAD scale was completed before and immediately after the invasive procedure.Results The score of anxiety and depression in younger women (<35 years of age) was (6.4±3.2) and (6.9±3.1), respectively, both of which were significantly higher than older women (≥35 year of age). The score of anxiety and depression in those with a low educational level (high school or below) was (6.8±3.4) and (7.4±2.9), respectively, both of which were significantly higher than women with a higher educational level (college degree or above). The score of anxiety before invasive procedure was (6.1±3.2), significantly higher than the score immediately after the procedure (5.2±2.7). Cognitive scores were negatively correlated with anxiety score (correlation coefficient: -0.3).Conclusion The invasive prenatal diagnostic procedures would confer some women with anxiety and depression. The degree of anxiety and depression was associated with age, educational level, and cognitive degree.
吴莉, 陈敏, 潘悦健, 赖峥菲, 郭晓玲, 陈敦金. 侵入性产前诊断对孕妇焦虑抑郁心理情况的影响[J]. 中国生育健康杂志, 2016, 27(3): 230-233.
WU Li, CHEN Min, PAN Yuejian, LAI Zhengfei, GUO Xiaoling, CHEN Dunjin. Assessment of maternal anxiety and depression levels before and after invasive prenatal diagnostic procedures. Chinese Journal of Reproductive Health, 2016, 27(3): 230-233.
1 Tabor A,Alfirevic Z.Update on procedure-related risks for prenatal diagnosis techniques.Fetal Diagn Ther,2010,27:1-7. 2 O’Connor TG,Winter MA,Hunn J,et al.Prenatal maternal anxiety predicts reduced adaptive immunity in infants.Brain Behav Immun,2013,32:21-28. 3 Qiu A,Rifkin-Graboi A,Chen H,et al.Maternal anxietyand infants' hippcampal development: timing matters.Transl Psychiatry,2013,3:e306. 4 DiPietro JA,Hilton SC,Hawkins M,et al.Maternal stress and affect influence fetal neurobehavioral development.Dev Psychol,2002,38:659-668. 5 Huizink AC,De Medina PR,Mulder EJH,et al.Psychological measures of prenatal stress as predictors of infant temperament.J Am Acad Child Adolesc Psychiatry,2002,41:1078-1085. 6 Buss C,Davis EP,Hobel CJ,et al.Maternal pregnancy-specific anxiety is associated with child executive function at 6-9 years age.Stress,2011,14:665-676. 7 Zigmond AS,Snaith RP.The hospital anxiety and depression scale.Acta Psychiatr Scand,1983,67:361-370. 8 Hoskovec J,Mastrobattista JM,Johnston D,et al.Anxiety and prenatal testing: do women with soft ultrasound findings have increased anxiety compared to women with other indications for testing?Prenat Diagn, 2008,28:135-140. 9 Bot-Robin V,Sendon S,Bourzoufi K,et al.Maternal anxiety and pain during prenatal diagnostic techniques: a prospective study.Prenat Diagn,2012,32:562-568. 10 徐志红,李怡巍,廖娟,等.超声引导下羊膜腔穿刺对孕妇心理影响的调查.西部医学,2012,24:1755-1757. 11 Al RA,Yalvac S,Altar OY,et al.Perceived pain and anxiety before and after amnio centesis among pregnant Turkish women.Clin Exp Obstet Gynecol,2009,36:184-186. 12 Ng CC,Lai FM,Yeo GS.Assessment of maternal anxiety levels before and after amniocentesis Singapore Med J,2004 ,45: 370-374. 13 Nakic Rados S,Kosec V,Gall V.The psychological effects of prenatal diagnostic procedures: maternal anxiety before and after invasive and noninvasive procedures.Prenat Diagn,2013,33:1194-1200. (