GDF1基因与先天性心脏病的相关性研究进展

张娟,吴青青

中国生育健康杂志 ›› 2017, Vol. 28 ›› Issue (2) : 192-194.

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中国生育健康杂志 ›› 2017, Vol. 28 ›› Issue (2) : 192-194.
综述

GDF1基因与先天性心脏病的相关性研究进展

  • 张娟,吴青青
作者信息 +
文章历史 +

摘要

先天性心脏病是最常见的先天性畸形类别,而GDF1是近年来发现的转化因子-β超家族成员之一,其定位于19p13.11,可通过多种信号通路调控心脏发育,在先天性心脏病的发生过程中起到了重要的调控作用,但其具体作用机制并不十分清楚。本文就GDF1基因与先天性心脏病的关联性及可能的作用机制进行综述。

关键词

生长分化因子1 / 先天性心脏病 / 信号通路 / 左右不对称模式

引用本文

导出引用
张娟,吴青青. GDF1基因与先天性心脏病的相关性研究进展[J]. 中国生育健康杂志, 2017, 28(2): 192-194

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基金

首都临床特色应用研究专项项目(Z141107002514006);北京市医院管理局“登峰”计划专项经费资助(DFL20151302)

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