Abstract：Objective To explore risk factors of female infertility with emphasis of work and environment exposures.Methods From October 8, 2012 to January 8, 2013, we conducted a questionnaire survey at the outpatient service in Peking University Third Hospital. The questionnaire included demographic information, personal habits, and exposure to some environmental factors. We took the female infertility as case group (n=352), while the natural pregnant women as control group (n=413).Results Univariate analysis revealed that two groups were different in some life style and environmental factors such as second-hand smoking, fried food intake, perfume use, working in the air-conditional environment, lack of exercises and some other factors. Unconditional Logistic regression analysis showed that the higher level of education, insomnia (OR=2.6, 95 % CI: 1.7~4.0), irregular menstruation (OR=3.1, 95 % CI: 1.8~5.3), fried foods (OR=2.0, 95 % CI: 1.2~3.3), the poor environmental residence (OR=1.9, 95 % CI: 1.4~2.7) and some other factors were risk factors for female infertility.Conclusion Female infertility is associated with life style and environmental factors. Reproductive health education should target these factors to reduce the risk of female infertility.
1 乐杰.妇产科学.第7版.北京:人民卫生出版社,2008:351-353. 2 Mascarenhas MN,Haxmar SR,Boerma T,et al.National,Regional,and Global Trends in infertility prevalence since 1990:a systematic analysis of 277 health surveys.PLoS Med,2012,9:e1001356. 3 高峻,高尔生.中国育龄妇女不孕率及其影响因素分析.中国卫生统计,2005,22:26-28. 4 封宗成,骆书秀,王卡琳,等.北流市已婚育龄夫妇不孕症调查分析.生殖与避孕,2013,33:280-283. 5 曹云飞.嘉兴市育龄夫妇不孕不育症的流行病学调查.中国现代医生,2012,50:25-27. 6 马兰,刘军莲,刘新敏.环境对女性生殖健康的影响.中国妇幼保健研究,2012,23:554-556. 7 Homan GF.The impact of lifestyle factors on reproductive performance in the general population and those undergoing infertility treatment:a review .Human Reproduction Update,2007,13:209-223. 8 梁红,朱林平,杨艳云.某炼钢厂接触噪声女工月经情况调查分析.广西中医药大学学报,2011,28:804-805. 9 Barron ML.Noise exposure,melatonin secretion,and menstrual cycle parameters:an integrative review.Biol Res Nurs,2007,9:49-69. 10 Marie P,Lise GA,Claire B,et al.Ambient air pollution and low birth weight:a European cohort study.Lancet,2013,S2213-2600:70192-70199. 11 Qiao J,Feng HL.Extra- and intra- ovarian factors in polycystic ovary syndrome:impact on oocyte maturation and embryo developmental competence.Hum Reprod Update,2011,17:17-33. 12 王冰冰.浅谈油炸食品对人体健康的影响.中国食物与营养,2010,8:74-77. 13 李晓琼,高存友,刘子霞,等.不孕症与健康行为相关因素的Logistic回归分析.实用医药杂志,2012,3:200-202.
