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血管内皮生长因子家族在妇产科若干疾病中的研究进展 |
杨舒奇, 黄明莉, 黄凌佳, 孙欣 |
150000 哈尔滨,哈尔滨医科大学附属第一医院产科 |
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摘要 血管内皮生长因子(VEGF)是一种高度特异性的促血管内皮细胞生长因子,在促进血管通透性增加、细胞外基质变性、血管内皮细胞迁移、增殖和血管形成等方面有着重要作用。同时,VEGF也可调节血管和淋巴管的生长,VEGF信号传导的失调与许多病理状态紧密相关,随着国内外研究人员对VEGF的深入研究,在妇产科领域包括肿瘤、复发性流产、子痫前期、胎儿生长受限(IUGR)等方面取得许多新的进展,本文就VEGF家族在妇产科几种常见疾病的新进展做一综述。
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关键词 :
血管内皮生长因子(VEGF),
肿瘤,
子痫前期,
复发性流产,
宫内生长受限(IUGR)
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收稿日期: 2018-10-22
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通讯作者:
黄明莉(doctor_hml@163.com)
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