Content of α-tocopherol and macronutrients in breast milk and associated factors
WU Ke, WANG Bei, ZHOU Lili, SHEN Liwei, CAI Meiqin
Department of Nutrition, School of Public Health, Shanghai Jiao Tong University, Shanghai 200025; Department of Obstetrics, Xinhua Hospital affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai 200092, China
Abstract：Objective To investigate the concentrations of breast milk macro-nutrients and α-tocopherol and to explore possible associations with maternal lipids metabolism. Methods Colostrum, transitional milk and mature milk were collected longitudinally from 89 healthy Shanghai lactating mothers of singleton, full-term delivery. The levels of macro-nutrients and α-tocopherol in human milk from different lactation stages were analyzed and compared. Perinatal medical history and blood biochemical data were also collected for correlation analysis. Results From colostrum to mature stage, breast milk α-tocopherol decreased sharply from 9.72 mg/L to 4.23 mg/L while lactose (from 7.54 mg/dL to 6.95 mg/dL) and protein decreased slightly (from 1.29 mg/dL to 0.99 mg/dL). However, fat content increased sharply from 1.58 mg/dL to 3.23 mg/dL. A positive correlation was found between milk fat and α-tocopherol concentrations during each lactation stage. Maternal BMI was positively correlated with the levels of α-tocopherol and fat in transitional milk. Maternal blood triglyceride was positively correlated with the levels of α-tocopherol in transitional milk. Meanwhile, no other correlations were observed. Conclusion Shanghai breast milk contained an abundant level of α-tocopherol, showing a positive correlation with milk fat content. Maternal long-term lipids metabolism may have an influence over milk composition, especially transitional milk.
吴轲, 王蓓, 周丽莉, 沈丽蔚, 蔡美琴. 母乳α-生育酚和宏量营养素水平及影响因素[J]. 中国生育健康杂志, 2020, 31(5): 414-419.
WU Ke, WANG Bei, ZHOU Lili, SHEN Liwei, CAI Meiqin. Content of α-tocopherol and macronutrients in breast milk and associated factors. Chinese Journal of Reproductive Health, 2020, 31(5): 414-419.
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