全球DOHaD理论研究的热点与前沿:基于CiteSpace的文献计量及可视化分析

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摘要目的解析全球健康和疾病的发育起源(DOHaD)理论的研究热点和前沿,为推动该领域研究持续发展提供参考。方法以2005—2020年间Web of Science收录的DOHaD理论相关文献作为研究对象,以Citespace软件为可视化工具,通过对国家、研究机构和关键词的共现分析以及突现词探测技术探索DOHaD理论的研究热点与前沿。结果最终纳入1 008篇有效文献。近年来,相关文献年发文量持续上升,英、美两国在该领域处于领先地位。当前研究的热点主题集中于生命早期营养不良相关健康结局、生物学机制以及胎儿期暴露。体外受精、氧化应激及内分泌干扰物是近年来该领域的研究前沿。结论全球DOHaD理论研究正处于发展阶段,健康结局、生物学机制、胎儿期暴露、体外受精、氧化应激以及内分泌干扰物是全球DOHaD领域内研究的热点和前沿。

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	徐韵涵
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	宋培歌

关键词 ： DOHaD理论, 可视化, Citespace, 热点, 前沿

Abstract：Objective To identify the hotspots and frontiers of studies about the Developmental Origins of Health and Disease(DOHaD) hypothesis, and to provide reference for further researches in the future. Methods Data of publications from 2005 to 2020 were retrieved from the Web of Science Core Collection database. CiteSpace software was used to analyze the hotspots and frontiers of DOHaD studies by identifying co-occurrences in the aspects of countries/regions, institutions and keywords and burst detection. Results A total of 1008 publications on DOHaD hypothesis were included. The annual number of the published articles has been rising. Most of the studies were from the United States, followed by England. The current research hotspots focused on adverse health outcomes associated to early-life malnutrition, biological mechanisms and fetal exposure. Meanwhile, in vitro fertilization, oxidative stress and endocrine disruptor were identified as three frontier topics. Conclusion Adverse health outcomes, biological mechanisms, fetal exposure, in vitro fertilization, oxidative stress and endocrine disruptor are the hotspots and frontiers of the current studies about DOHaD hypothesis.

Key words： DOHaD hypothesis visualization CiteSpace hotspots frontiers

收稿日期: 2021-09-06

ZTFLH:

R17

基金资助:国家自然科学基金(72104211)

通讯作者: 宋培歌(peigesong@zju.edu.cn)

引用本文:

徐韵涵, 安琳, 朱思雨, 叶欣欣, 奕倩, 冯燕, 周一敏, 张丹, 宋培歌. 全球DOHaD理论研究的热点与前沿:基于CiteSpace的文献计量及可视化分析[J]. 中国生育健康杂志, 2023, 34(3): 212-217. XU Yunhan, AN Lin, ZHU Siyu, YE Xinxin, YI Qian, FENG Yan, ZHOU Yimin, ZHANG Dan, SONG Peige. Hotspots and frontiers of studies about DOHaD hypothesis:A bibliometric and visual analysis based on CiteSpace. Chinese Journal of Reproductive Health, 2023, 34(3): 212-217.

链接本文:

http://cjrh.bjmu.edu.cn/CN/ 或 http://cjrh.bjmu.edu.cn/CN/Y2023/V34/I3/212

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