自发性早产预测的研究进展

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摘要早产是最常见的妊娠并发症,是新生儿死亡的主要原因。自发性早产占早产病例的65%~70%,其确切病因至今未明。尽管已大力推广宫缩抑制剂等治疗措施,加强胎儿监护和产前检查,但是自发性早产的发生率并没有明显下降。干预时间过晚是目前导致自发性早产防治效果不满意的主要原因之一。早产病因学复杂,从而导致其预测筛选困难,治疗也缺乏针对性。筛选与确定便捷、准确和无创伤的早产预测因子及诊断方法,探索与运用恰当、先进的统计学方法,建立高灵敏度和特异度的早产预警机制,是当前产科研究的热点和难点之一。因此,本研究对早产的预测因子以及预测模型的国内外进展进行综述。

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	杨雅琴
	李佳慧
	赵莉萍
	张乐
	李智文
	叶荣伟

关键词 ：自发性早产, 预测, 模型, 进展

收稿日期: 2022-10-25

ZTFLH:	R17
	R71

基金资助:内蒙古自治区“十四五”社会公益领域重点研发和成果转化计划(2023YFSH0051); 国家自然科学基金委员会面上项目(81673177,82173527); 北京市自然科学基金委员会面上项目(7222248)

通讯作者: 赵莉萍(zhaoyehong@sogou.com);张乐(zhangle@bjmu.edu.cn)

引用本文:

杨雅琴, 李佳慧, 赵莉萍, 张乐, 李智文, 叶荣伟. 自发性早产预测的研究进展[J]. 中国生育健康杂志, 2023, 34(5): 492-497.

链接本文:

http://cjrh.bjmu.edu.cn/CN/ 或 http://cjrh.bjmu.edu.cn/CN/Y2023/V34/I5/492

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