妊娠期糖、脂代谢特点及与妊娠期高血压疾病和远期心血管疾病关系的研究进展

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摘要近年来随着我国二胎政策的开放、孕产妇年龄的增加,妊娠期高血压疾病的发病率呈现上升趋势。妊娠母体的物质代谢变化不仅可以满足母体和胎儿的生理需求,而且对妊娠期疾病和远期心血管疾病可能存在潜在影响。目前越来越多的研究表明,妊娠期高血压疾病与妊娠期母体不同阶段糖、脂代谢变化存在相同的病理基础,基于这些领域的基础和临床的新进展,综述了妊娠期糖、脂代谢变化与妊娠期高血压疾病及远期心血管疾病的关系,以期为孕产妇的妊娠期高血压疾病和远期心血管疾病的评估、随访和改善女性产后心血管健康提供新思路。

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	刘超
	蔡伟
	陈少伯

关键词 ：妊娠期高血压疾病, 糖代谢, 脂代谢, 心血管疾病

收稿日期: 2020-11-23

ZTFLH:	R17
	R71

基金资助:天津市科技计划项目(16ZXMJSY00130)

通讯作者: 刘超(doctorlc80@163.com)

引用本文:

刘超, 蔡伟, 陈少伯. 妊娠期糖、脂代谢特点及与妊娠期高血压疾病和远期心血管疾病关系的研究进展[J]. 中国生育健康杂志, 2022, 33(5): 491-494.

链接本文:

http://cjrh.bjmu.edu.cn/CN/ 或 http://cjrh.bjmu.edu.cn/CN/Y2022/V33/I5/491

1 Webster K,Fishburn S,Maresh M,et al.Diagnosis and management of hypertension in pregnancy:summary of updated NICE guidance.BMJ,2019,366:l5119.
2 杨宁,李玉明.宽严相济:孕期血压管理.中华高血压杂志,2019,27:2-4.
3 Hauspurg A,Countouris ME,Catov JM.Hypertensive disorders of pregnancy and future maternal health:How can the evidence guide postpartum management? Curr Hypertens Rep,2019,21:96.
4 Stang J,Huffman LG.Position of the academy of nutrition and dietetics:Obesity,reproduction,and pregnancy outcomes.J Acad Nutr Diet,2016,116:677-691.
5 蔡伟,李玉明.孕期心血管风险暴露与母子两代心血管代谢风险的相关关系.循证医学,2018,18:13-18+22.
6 Kampmann U,Knorr S,Fuglsang J,et al.Determinants of maternal insulin resistance during pregnancy:An updated overview.J Diabetes Res,2019,2019:5320156.
7 Sirota I,Stein DE,Vega M,et al.Insulin resistance and β-cell function calculated by homeostasis model assessment in lean,overweight,and obese women with polycystic ovary syndrome.J Reprod Med,2016,61:3-10.
8 Feng Y,Feng Q,Lv Y,et al.The relationship between iron metabolism,stress hormones,and insulin resistance in gestational diabetes mellitus.Nutr Diabetes,2020,10:17.
9 Hao S,You J,Chen L,et al.Changes in pregnancy-related serum biomarkers early in gestation are associated with later development of preeclampsia.PLoS One,2020,15:e0230000.
10 Kautzky-Willer A,Pacini G,Tura A,et al.Increased plasma leptin in gest ational diabetes.Diabetologia,2001,44:164-172.
11 成丽岚,成叶利,马爱江,等.OXLDL,TGF-β2,APN,瘦素及ApoC Ⅲ与妊娠合并糖尿病的相关性研究.中国医药导报,2018,15:73-77.
12 Simpson S,Smith L,Bowe J.Placental peptides regulating islet adaptation to pregnancy:clinical potential in gestational diabetes mellitus.Curr Opin Pharmacol,2018,43:59-65.
13 Mate A,Blanca AJ,Salsoso R,et al.Insulin therapy in pregnancy hypertensive diseases and its effect on the offspring and mother later in life.Curr Vasc Pharmacol,2019,17:455-464.
14 马征戈,李春擎,李江华,等.妊娠期糖尿病患者不同血糖控制水平对胎儿心脏结构和功能的影响.山东医药,2020,60:57-59.
15 Jiménez-Moleón JJ,Bueno-Cavanillas A,Luna-del-Castillo Jde D,et al.Impact of different levels of carbohydrate intolerance on neonatal outcomes classically associated with gestational diabetes mellitus.Eur J Obstet Gynecol Reprod Biol,2002,102:36-41.
16 南燕燕,李娜,李岩,等.孕期血脂水平对妊娠期并发症及子代的影响.中国计划生育和妇产科,2019,11:63-66,71.
17 Larsen TD,Sabey KH,Knutson A J,et al.Diabetic pregnancy and maternal high-fat diet impair mitochondrial dynamism in the developing fetal rat heart by sex-specific mechanisms.Int J Mol Sci,2019,20:3090.
18 郑君,彭菊生,饶敏.孕期血清脂溶性维生素及血脂水平与妊娠期高血压疾病关系.中国计划生育学杂志,2019,27:994-997.
19 Johnson ML,Saffrey MJ,Taylor VJ.Gastrointestinal capacity,gut hormones and appetite change during rat pregnancy and lactation.Reproduction,2019,157:431-443.
20 Most J,Dervis S,Haman F,et al.Energy intake requirements in pregnancy.Nutrients,2019,11:1812.
21 Kampmann U,Knorr S,Fuglsang J,et al.Determinants of maternal insulin resistance during pregnancy:An updated overview.J Diabetes Res,2019,2019,5320156.
22 Marcus Y,Shefer G,Stern N.Adipose tissue renin-angiotensin-aldosterone system(RAAS) and progression of insulin resistance.Mol Cell Endocrinol,2013,378:1-14.
23 Longo M,Refuerzo JS,Mann L,et al.Adverse effect of high-fat diet on metabolic programming in offspring born to a murine model of maternal hypertension.Am J Hypertens,2016,29:1366-1373.
24 Lin YS,Tang CH,Yang CY,et al.Effect of pre-eclampsia-eclampsia on major cardiovascular events among peripartum women in Taiwan .Am J Cardiol,2011,107:325-330.
25 Alonso-Ventura V,Li Y,Pasupuleti V,et al.Effects of preeclampsia and eclampsia on maternal metabolic and biochemical outcomes in later life:a systematic review and meta-analysis.Metabolism,2020,102:154012.
26 周旋,汲宝兰,满冬梅,等.胰岛素治疗与妊娠期糖尿病患者孕期体重及体重指数增加的相关性.浙江医学,2019,41:58-60.
27 Estienne A,Bongrani A,Reverchon M,et al.Involvement of novel adipokines,chemerin,visfatin,resistin and apelin in reproductive functions in normal and pathological conditions in humans and animal models.Int J Mol Sci,2019,20:4431.
28 陈鹏,史琳,杨红梅,等.妊娠期高血压、子痫前期及子痫与孕前和孕期体质量及其他因素的相关性研究.实用妇产科杂志,2017,33:848-852.
29 王艳,查文慧,陈洋,等.妊娠期糖尿病与妊娠期高血压疾病病理机制的相关性.国际生殖健康/计划生育杂志,2020,39:63-66.
30 Brewster S,Zinman B,Retnakaran R,et al.Cardiometabolic consequences of gestational dysglycemia.J Am Coll Cardiol,2013,62:677-684.
31 Pace R,Brazeau AS,Meltzer S,et al.Conjoint associations of gestational diabetes and hypertension with diabetes,hypertension,and cardiovascular disease in parents:A retrospective cohort study.Am J Epidemiol,2017,186:1115-1124.
32 Bellamy L,Casas JP,Hingorani AD,et al.Type 2 diabetes mellitus after gestational diabetes:a systematic review and meta-analysis.Lancet,2009,373:1773-1779.
33 Li LJ,Aris IM,Su LL,et al.Effect of gestational diabetes and hypertensive disorders of pregnancy on postpartum cardiometabolic risk.Endocr Connect,2018,7:433-442.