肌醇预防妊娠期糖尿病的Meta分析

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摘要肌醇是一种天然存在的营养物质,广泛存在于谷物、玉米、豆类和肉类中。研究发现,肌醇可能作为一种潜在有益的补充剂用于预防妊娠期糖尿病(GDM)发生,孕期服用肌肉肌醇可以显著降低GDM的发生率,并可改善糖耐量异常,增强胰岛素敏感性,减少早产、巨大儿和妊娠期高血压的发生。近年来,国内外关于孕期口服肌醇预防GDM的随机对照试验(RCT)研究逐渐增多,但取得的临床效果存在一定的争议。本文系统性地回顾了9项有关肌醇预防GDM的RCT进行Meta分析,以期评价孕期口服肌醇预防GDM的临床效果。

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	纳继根
	陈慧婷
	李楠
	NicholasD.E.Greene
	李智文

关键词 ：妊娠期糖尿病(GDM), 肌醇, Meta分析, 随机对照试验

收稿日期: 2021-10-27

ZTFLH:

R17

基金资助:英国医学研究理事会基金(MR/T003847/1)

通讯作者: 李智文(lizw@bjmu.edu.cn);李楠(linan01@pku.edu.cn)

作者简介: ^▲共同第一作者

引用本文:

纳继根, 陈慧婷, 李楠, NicholasD.E.Greene, 李智文. 肌醇预防妊娠期糖尿病的Meta分析[J]. 中国生育健康杂志, 2023, 34(4): 381-387.

链接本文:

http://cjrh.bjmu.edu.cn/CN/ 或 http://cjrh.bjmu.edu.cn/CN/Y2023/V34/I4/381

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