产前强化饮食联合体力活动干预对妊娠期糖尿病孕妇脂代谢、血清内脂素和丝氨酸蛋白酶抑制因子水平及母婴结局的影响

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摘要目的探讨产前强化饮食联合体力活动干预对妊娠期糖尿病(GDM)孕妇脂代谢、血清内脂素(Visfatin)和丝氨酸蛋白酶抑制因子(Vaspin)水平及母婴结局的影响。方法选取2020年5月至2021年12月120例GDM孕妇,年龄20~35岁,孕周24~28周,简单随机分为联合组和对照组各60例。对照组孕妇进行常规健康教育,联合组孕妇在常规健康教育的基础上进行产前强化饮食联合体力活动干预。比较两组孕妇的血糖、血脂、血清Visfatin、Vaspin、母婴结局。结果干预后,联合组的空腹血糖、餐后2 h血糖低于对照组(P＜0.05)。联合组的血浆TC、TG、LDL-C水平低于对照组,血浆HDL-C水平高于对照组(P＜0.05)。联合组的血清Visfatin、Vaspin水平低于对照组(P＜0.05)。联合组剖宫产、羊水过多、早产、胎儿宫内窘迫、巨大儿的比例低于对照组(P＜0.05)。结论产前强化饮食联合体力活动干预有利于调节GDM孕妇的脂代谢,降低血清Visfatin、Vaspin水平,血糖控制效果良好,显著改善母婴结局。

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	李海莲
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关键词 ：妊娠期糖尿病(GDM), 脂代谢, 内脂素(Visfatin), 丝氨酸蛋白酶抑制因子(Vaspin), 母婴结局

收稿日期: 2022-09-20

ZTFLH:

R17

基金资助:河北省卫健委项目(20221438)

作者简介: ^▲共同第一作者

引用本文:

李海莲, 李海香, 赵明霞. 产前强化饮食联合体力活动干预对妊娠期糖尿病孕妇脂代谢、血清内脂素和丝氨酸蛋白酶抑制因子水平及母婴结局的影响[J]. 中国生育健康杂志, 2024, 35(2): 184-187.

链接本文:

http://cjrh.bjmu.edu.cn/CN/ 或 http://cjrh.bjmu.edu.cn/CN/Y2024/V35/I2/184

1 Juan J,Yang H.Prevalence,prevention,and lifestyle intervention of gestational diabetes mellitus in China.Int J Environ Res Public Health,2020,17:9517-9520.
2 Lende M,Rijhsinghani A.Gestational diabetes:overview with emphasis on medical management.Int J Environ Res Public Health,2020,17:9573-9576.
3 Hu Z,Tian Y,Li J,et al.Coagulation index and pregnancy outcome in gestational diabetes mellitus.Clin Lab,2021,67:336-340.
4 Mistry SK,Gupta R,Alam S,et al.Gestational diabetes mellitus (GDM) and adverse pregnancy outcome in South Asia:A systematic review.Endocrinol Diabetes Metab,202,4:285-288.
5 Mizgier M,Jarzabek-Bielecka G,Mruczyk K.Maternal diet and gestational diabetes mellitus development.J Matern Fetal Neonatal Med,2021,34:77-86.
6 Filardi T,Panimolle F,Crescioli C,et al.Gestational diabetes mellitus:the impact of carbohydrate quality in diet.Nutrients,2019,11:1549-1552.
7 Rasmussen L,Poulsen CW,Kampmann U,et al.Diet and healthy lifestyle in the management of gestational diabetes mellitus.Nutrients,2020,12:3050-3053.
8 Ehrlich SF,Ferrara A,Hedderson MM,et al.Exercise during the first trimester of pregnancy and the risks of abnormal screening and gestational diabetes mellitus.Diabetes Care,2021,44:425-432.
9 Abdel-Fadeil MR,Abd Allah E,Iraqy HM,et al.Experimental obesity and diabetes reduce male fertility:Potential involvement of hypothalamic Kiss-1,pituitary nitric oxide,serum vaspin and visfatin.Pathophysiology,2019,26:181-189.
10 魏小辉,王育璠.2015年国际妇产科联盟(FIGO)妊娠期糖尿病诊疗指南解读.中华内分泌代谢杂志,2016,32:895-899.11 方积乾.生物医学研究的统计方法.北京:高等教育出版社,2007:288.
12 中国营养学会.中国居民膳食营养素参考摄入量.营养学报,2001,3:193-196.
13 MacPherson M,Cranston K,Locke S,et al.Diet and exercise interventions for individuals at risk for type 2 diabetes:a scoping review protocol.BMJ Open,2020,10:3953-3956.
14 刘燕.饮食干预联合运动指导对妊娠期糖尿病患者血糖水平的影响.川北医学院学报,2022,37:133-136.
15 王欣.运动疗法+饮食疗法用于妊娠期糖尿病的临床价值.中国医药指南,2022,20:45-48.
16 Dakroub A,Nasser SA,Kobeissy F,et al.Visfatin:An emerging adipocytokine bridging the gap in the evolution of cardiovascular diseases.J Cell Physiol,2021,236:6282-6296.
17 Yang HW,Huang YG,Gai CL,et al.Serumvaspin levels are positively associated with diabetic retinopathy in patients with type 2 diabetes mellitus.J Diabetes Investig,2021,12:566-573.
18 梁锦伦,梁媚珍,刘凤琼.血清Vaspin与妊娠期糖尿病孕妇母婴结局的关系研究.医学理论与实践,2022,35:458-460.
19 Radzicka S,Pietryga M,Iciek R,et al.The role of visfatin in pathogenesis of gestational diabetes (GDM).Ginekol Pol,2018,89:518-521.
20 Kumari B,Yadav UCS.Adipokinevisfatin′s role in pathogenesis of diabesity and related metabolic derangements.Curr Mol Med,2018,18:116-125.
21 Koivunen S,Viljakainen M,Männistö T,et al.Pregnancy outcomes according to the definition of gestational diabetes.PLoS One,2020,15:2294-2296.
22 Zehravi M,Maqbool M,Ara I.Correlation between obesity,gestational diabetes mellitus,and pregnancy outcomes:an overview.Int J Adolesc Med Health,2021,33:339-345.
23 吴锦霞.饮食及运动方案控制体质量对妊娠期糖尿病患者妊娠结局及顺产率的临床效果探讨.糖尿病新世界,2021,24:36-42.
24 张庆环,徐一玲.运动疗法联合饮食干预对妊娠期糖尿病患者血糖控制及母婴结局的影响.数理医药学杂志,2021,34:1543-1545.
25 Lust O,Chongsuwat T,Lanham E,et al.Does exercise prevent gestational diabetes mellitus in pregnant women? A Clin-IQ.J Patient Cent Res Rev,2021,8:281-285.